Tuning SpyTag–SpyCatcher mutant pairs toward orthogonal reactivity encryption† †Electronic supplementary information (ESI) available: Supporting figures, molecular cloning, protein expression and purification protocols, protein sequences and other molecular characterizations. See DOI: 10.1039/c7sc02686b Click here for additional data file.

Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling† †Electronic supplementary information (ESI) available: Full experimental details, synthesis and characterizations of compounds, supplementary data, figures and references. See DOI: 10.1039/c7sc00284j Click here for additional data file. Click here for additional data file.

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate† †Electronic supplementary information (ESI) available: Experimental procedures and compound characterizations (PDF). CCDC 1041425 (3fb). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04135c Click here for additional data file. Click here for additional data file.

Beijing National Laboratory for Molecular S Recognition and Function, Institute of Chemi 100190, China. E-mail: [email protected] Marine College, Shandong University at We 264209, China. E-mail: [email protected] University of Chinese Academy of Sciences, † Electronic supplementary information ( and compound characterizations (PDF) crystallographic data in CIF or o 10.1039/c6sc04135c ‡ X.-Y. C...

Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe† †Electronic supplementary information (ESI) available: Experimental section and supporting figures. See DOI: 10.1039/c5sc03600c Click here for additional data file.

Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates† †Electronic supplementary information (ESI) available: Supporting figures, synthesis and characterisation of the substrates, and enzymatic assays. See DOI: 10.1039/c5mb00730e Click here for additional data file.

Synthesis and stabilities of peptide-based [1]rotaxanes: molecular grafting onto lasso peptide scaffolds† †Electronic supplementary information (ESI) available: Experimental procedures and analytical data of all new compounds. CCDC 1520783. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00021a Click here for additional data file. Click here for additional data file.